The p53 knowledgebase: an integrated information resource for p53 research

KBase: An Integrated Knowledgebase for Predictive Biology and Environmental Research

The General Information of the Tumor Suppressor Gene p53 and the Protein p53

This paper talks about the history of the human gene p53 and some important events since it’s discovered in 1979. It also shows the detailed structure of the human gene p53 and the protein p53 which is encoded by the gene TP53. The proteins contain three major domain, N-terminal domain, DNA binding domain and C-terminal domain, each contains unique structure and function. Last, it describes the...

Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research

Frequent outbreaks of highly pathogenic avian influenza and the increasing data available for comparative analysis require a central database specialized in influenza viruses (IVs). We have established the Influenza Virus Database (IVDB) to integrate information and create an analysis platform for genetic, genomic, and phylogenetic studies of the virus. IVDB hosts complete genome sequences of i...

An Integrated Human Information Behavior Research Framework for Information Studies

Human information behavior is emerging as an important component of information studies. As in many emerging research areas, one challenge is to identify important facets of human information behavior and understand how different methods can be best used to research these facets. This paper presents the framework of an approach to designing and synthesizing research studies in human information...

Protein kinase resource: an integrated environment for phosphorylation research.

The protein kinase superfamily is an important group of enzymes controlling cellular signaling cascades. The increasing amount of available experimental data provides a foundation for deeper understanding of details of signaling systems and the underlying cellular processes. Here, we describe the Protein Kinase Resource, an integrated online service that provides access to information relevant ...